Pentacyclic Triterpenoids Inhibit IKKβ Mediated Activation of NF-κB Pathway: In Silico and In Vitro Evidences

Pentacyclic Triterpenoids (PTs) and their analogues as well as derivatives are emerging as important drug leads for various diseases. They act through a variety of mechanisms and a majority of them inhibit the nuclear factor kappa-beta (NF-κB) signaling pathway. In this study, we examined the effect...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Patil, Kalpesh R., Mohapatra, Purusottam, Patel, Harun M., Goyal, Sameer N., Ojha, Shreesh, Kundu, Chanakya N., Patil, Chandragouda R.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418667/
https://ncbi.nlm.nih.gov/pubmed/25938234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125709
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