In vivo and in vitro protective effects of omeprazole against neuropathic pain

Apart from reducing the acid secretion, omeprazole inhibits activation of the nuclear factor-κB, release of inflammatory cytokines, and chemotaxis of neutrophils. These mechanisms prompted us to evaluate antineuropathic effect of omeprazole in the chronic constriction injury (CCI)-induced rat model...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chanchal, Sanjay K., Mahajan, Umesh B., Siddharth, Sumit, Reddy, Navyya, Goyal, Sameer N., Patil, Prakash H., Bommanahalli, Basavaraj P., Kundu, Chanakya N., Patil, Chandragouda R., Ojha, Shreesh
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951708/
https://ncbi.nlm.nih.gov/pubmed/27435304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30007
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