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Calpain-1 induces endoplasmic reticulum stress in promoting cardiomyocyte apoptosis following hypoxia/reoxygenation

Both calpain activation and endoplasmic reticulum (ER) stress are implicated in ischemic heart injury. However, the role of calpain in ER stress remains largely elusive. This study investigated whether calpain activation causes ER stress, thereby mediating cardiomyocyte apoptosis in an in vitro mode...

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Foilsithe in:Biochim Biophys Acta
Main Authors: Zheng, Dong, Wang, Grace, Li, Shuai, Fan, Guo-Chang, Peng, Tianqing
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418534/
https://ncbi.nlm.nih.gov/pubmed/25660447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2015.01.019
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