The superoxide anion donor, potassium superoxide, induces pain and inflammation in mice through production of reactive oxygen species and cyclooxygenase-2

It is currently accepted that superoxide anion (O(2) (•−)) is an important mediator in pain and inflammation. The role of superoxide anion in pain and inflammation has been mainly determined indirectly by modulating its production and inactivation. Direct evidence using potassium superoxide (KO(2)),...

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Vydáno v:Braz J Med Biol Res
Hlavní autoři: Maioli, N.A., Zarpelon, A.C., Mizokami, S.S., Calixto-Campos, C., Guazelli, C.F.S., Hohmann, M.S.N., Pinho-Ribeiro, F.A., Carvalho, T.T., Manchope, M.F., Ferraz, C.R., Casagrande, R., Verri, W.A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Associação Brasileira de Divulgação Científica 2015
Témata:
Biomedical Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418362/
https://ncbi.nlm.nih.gov/pubmed/25714890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20144187
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