Semaglutide, a Once-Weekly Human GLP-1 Analog, Does Not Reduce the Bioavailability of the Combined Oral Contraceptive, Ethinylestradiol/Levonorgestrel

The effect of semaglutide, a once-weekly human glucagon-like peptide-1 (GLP-1) analog in development for type 2 diabetes (T2D), on the bioavailability of a combined oral contraceptive was investigated. Postmenopausal women with T2D (n = 43) on diet/exercise ± metformin received ethinylestradiol (0.0...

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Vydáno v:J Clin Pharmacol
Hlavní autoři: Kapitza, Christoph, Nosek, Leszek, Jensen, Lene, Hartvig, Helle, Jensen, Christine B, Flint, Anne
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2015
Témata:
Drug Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418331/
https://ncbi.nlm.nih.gov/pubmed/25475122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.443
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