Myeloperoxidase Is Increased in Human Cerebral Aneurysms and Increases Formation and Rupture of Cerebral Aneurysms in Mice

BACKGROUND AND PURPOSE: Cerebral aneurysm (CA) affects 3% of the population and is associated with hemodynamic stress and inflammation. Myeloperoxidase (MPO), a major oxidative enzyme associated with inflammation, is increased in CA patients, but whether MPO contributes to CA is not known. We tested...

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Vydáno v:Stroke
Hlavní autoři: Chu, Yi, Wilson, Katina, Gu, He, Wegman-Points, Lauren, Dooley, Sarah A., Pierce, Gary L., Cheng, Guangjie, Pena Silva, Ricardo A., Heistad, Donald D., Hasan, David
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418183/
https://ncbi.nlm.nih.gov/pubmed/25922506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.114.008589
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