IL-2 Inducible T-cell Kinase, a Novel Therapeutic Target in Melanoma

PURPOSE: Interleukin-2 inducible T-cell kinase (ITK) promoter CpG sites are hypomethylated in melanomas compared to nevi. The expression of ITK in melanomas, however, has not been established and requires elucidation. EXPERIMENTAL DESIGN: An ITK specific monoclonal antibody was used to probe section...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Clin Cancer Res
मुख्य लेखकों: Carson, Craig C., Moschos, Stergios J., Edmiston, Sharon N., Darr, David B., Nikolaishvili-Feinberg, Nana, Groben, Pamela A., Zhou, Xin, Kuan, Pei Fen, Pandey, Shaily, Chan, Keefe T., Jordan, Jamie L., Hao, Honglin, Frank, Jill S., Hopkinson, Dennis A., Gibbs, David C., Alldredge, Virginia D., Parrish, Eloise, Hanna, Sara C., Berkowitz, Paula, Rubenstein, David S., Miller, C. Ryan, Bear, James E., Ollila, David W., Sharpless, Norman E., Conway, Kathleen, Thomas, Nancy E.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2015
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418029/
https://ncbi.nlm.nih.gov/pubmed/25934889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-1826
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