Downmodulation of Vaccine-Induced Immunity and Protection against the Intracellular Bacterium Francisella tularensis by the Inhibitory Receptor FcγRIIB

Fc gamma receptor IIB (FcγRIIB) is the only Fc gamma receptor (FcγR) which negatively regulates the immune response, when engaged by antigen- (Ag-) antibody (Ab) complexes. Thus, the generation of Ag-specific IgG in response to infection or immunization has the potential to downmodulate immune prote...

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發表在:J Immunol Res
Main Authors: Franz, Brian J., Li, Ying, Bitsaktsis, Constantine, Iglesias, Bibiana V., Pham, Giang, Sunagar, Raju, Kumar, Sudeep, Gosselin, Edmund J.
格式: Artigo
語言:Inglês
出版: Hindawi Publishing Corporation 2015
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417568/
https://ncbi.nlm.nih.gov/pubmed/25961064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/840842
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