Downmodulation of Vaccine-Induced Immunity and Protection against the Intracellular Bacterium Francisella tularensis by the Inhibitory Receptor FcγRIIB

Fc gamma receptor IIB (FcγRIIB) is the only Fc gamma receptor (FcγR) which negatively regulates the immune response, when engaged by antigen- (Ag-) antibody (Ab) complexes. Thus, the generation of Ag-specific IgG in response to infection or immunization has the potential to downmodulate immune prote...

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Bibliographic Details
Published in:J Immunol Res
Main Authors: Franz, Brian J., Li, Ying, Bitsaktsis, Constantine, Iglesias, Bibiana V., Pham, Giang, Sunagar, Raju, Kumar, Sudeep, Gosselin, Edmund J.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417568/
https://ncbi.nlm.nih.gov/pubmed/25961064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/840842
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