Induction of ER stress-mediated apoptosis by ceramide via disruption of ER Ca(2+) homeostasis in human adenoid cystic carcinoma cells

BACKGROUND: Ceramides are a class of sphingolipids that form the structural component of the cell membrane and also act as second messengers in cell signaling pathways. Emerging results suggest that ceramide induces growth arrest and apoptosis in various human cancer cells. However, the mechanisms u...

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Опубликовано в: :Cell Biosci
Главные авторы: Liu, Zhe, Xia, Yichao, Li, Bo, Xu, Hui, Wang, Chenxing, Liu, Ying, Li, Yi, Li, Chunjie, Gao, Ning, Li, Longjiang
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2014
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417540/
https://ncbi.nlm.nih.gov/pubmed/25937892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-4-71
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