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Plumbagin inhibits prostate carcinogenesis in intact and castrated PTEN knockout mice via targeting PKCε, Stat3 and epithelial to mesenchymal transition markers

Prostate cancer (PCa) continues to remain the most common cancer and the second leading cause of cancer-related deaths in American males. The Pten deletions and/or mutations are frequently observed in both primary prostate cancers and metastatic prostate tissue samples. Pten deletion in prostate epi...

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Detalhes bibliográficos
Publicado no:Cancer Prev Res (Phila)
Main Authors: Hafeez, Bilal Bin, Fischer, Joseph W., Singh, Ashok, Zhong, Weixiong, Mustafa, Ala, Meske, Louise, Sheikhani, Mohammad Ozair, Verma, Ajit Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417441/
https://ncbi.nlm.nih.gov/pubmed/25627799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-14-0231
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