A universal strategy for regulating mRNA translation in prokaryotic and eukaryotic cells

We describe a simple strategy to control mRNA translation in both prokaryotic and eukaryotic cells which relies on a unique protein–RNA interaction. Specifically, we used the Pumilio/FBF (PUF) protein to repress translation by binding in between the ribosome binding site (RBS) and the start codon (i...

Full description

Saved in:
Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Cao, Jicong, Arha, Manish, Sudrik, Chaitanya, Mukherjee, Abhirup, Wu, Xia, Kane, Ravi S.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
Subjects:
Synthetic Biology and Bioengineering
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417184/
https://ncbi.nlm.nih.gov/pubmed/25845589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv290
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items