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Significance of ligand interactions involving Hop2-Mnd1 and the RAD51 and DMC1 recombinases in homologous DNA repair and XX ovarian dysgenesis

The evolutionarily conserved Hop2-Mnd1 complex is a key cofactor for the meiosis-specific recombinase Dmc1. However, emerging evidence has revealed that Hop2-Mnd1 is expressed in somatic tissues, primary human fibroblasts and cell lines, and that it functions in conjunction with the Rad51 recombinas...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Zhao, Weixing, Sung, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417169/
https://ncbi.nlm.nih.gov/pubmed/25820426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv259
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