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The NEIL glycosylases remove oxidized guanine lesions from telomeric and promoter quadruplex DNA structures

G-quadruplex is a four-stranded G-rich DNA structure that is highly susceptible to oxidation. Despite the important roles that G-quadruplexes play in telomere biology and gene transcription, neither the impact of guanine lesions on the stability of quadruplexes nor their repair are well understood....

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Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Zhou, Jia, Fleming, Aaron M., Averill, April M., Burrows, Cynthia J., Wallace, Susan S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417164/
https://ncbi.nlm.nih.gov/pubmed/25813041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv252
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