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Transcriptional Regulation of GAD1 GABA Synthesis Gene in the Prefrontal Cortex of Subjects with Schizophrenia
Expression of GAD1 GABA synthesis enzyme is highly regulated by neuronal activity and reaches mature levels in prefrontal cortex not before adolescence. A significant portion of cases diagnosed with schizophrenia show deficits in GAD1 RNA and protein levels in multiple areas of adult cerebral cortex...
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| Veröffentlicht in: | Schizophr Res |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4417100/ https://ncbi.nlm.nih.gov/pubmed/25458568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2014.10.020 |
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