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Structure based approaches for targeting non-coding RNAs with small molecules
The increasing appreciation of the central role of non-coding RNAs (miRNAs and long non coding RNAs) in chronic and degenerative human disease makes them attractive therapeutic targets. This would not be unprecedented: the bacterial ribosomal RNA is a mainstay for antibacterial treatment, while the...
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| Veröffentlicht in: | Curr Opin Struct Biol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4416997/ https://ncbi.nlm.nih.gov/pubmed/25687935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2015.01.008 |
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