Arginine dependence of acute myeloid leukemia blast proliferation: a novel therapeutic target

Acute myeloid leukemia (AML) is one of the most common acute leukemias in adults and children, yet significant numbers of patients relapse and die of disease. In this study, we identify the dependence of AML blasts on arginine for proliferation. We show that AML blasts constitutively express the arg...

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Detaylı Bibliyografya
Yayımlandı:Blood
Asıl Yazarlar: Mussai, Francis, Egan, Sharon, Higginbotham-Jones, Joseph, Perry, Tracey, Beggs, Andrew, Odintsova, Elena, Loke, Justin, Pratt, Guy, U, Kin Pong, Lo, Anthony, Ng, Margaret, Kearns, Pamela, Cheng, Paul, De Santo, Carmela
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2015
Konular:
Myeloid Neoplasia
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416943/
https://ncbi.nlm.nih.gov/pubmed/25710880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-09-600643
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