Passive Immunization with Phospho-Tau Antibodies Reduces Tau Pathology and Functional Deficits in Two Distinct Mouse Tauopathy Models

In Alzheimer’s disease (AD), an extensive accumulation of extracellular amyloid plaques and intraneuronal tau tangles, along with neuronal loss, is evident in distinct brain regions. Staging of tau pathology by postmortem analysis of AD subjects suggests a sequence of initiation and subsequent sprea...

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Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Sankaranarayanan, Sethu, Barten, Donna M., Vana, Laurel, Devidze, Nino, Yang, Ling, Cadelina, Gregory, Hoque, Nina, DeCarr, Lynn, Keenan, Stefanie, Lin, Alan, Cao, Yang, Snyder, Bradley, Zhang, Bin, Nitla, Magdalena, Hirschfeld, Gregg, Barrezueta, Nestor, Polson, Craig, Wes, Paul, Rangan, Vangipuram S., Cacace, Angela, Albright, Charles F., Meredith, Jere, Trojanowski, John Q., Lee, Virginia M-Y., Brunden, Kurt R., Ahlijanian, Michael
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2015
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416899/
https://ncbi.nlm.nih.gov/pubmed/25933020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125614
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