The Class III Cyclobutane Pyrimidine Dimer Photolyase Structure Reveals a New Antenna Chromophore Binding Site and Alternative Photoreduction Pathways

Photolyases are proteins with an FAD chromophore that repair UV-induced pyrimidine dimers on the DNA in a light-dependent manner. The cyclobutane pyrimidine dimer class III photolyases are structurally unknown but closely related to plant cryptochromes, which serve as blue-light photoreceptors. Here...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Scheerer, Patrick, Zhang, Fan, Kalms, Jacqueline, von Stetten, David, Krauß, Norbert, Oberpichler, Inga, Lamparter, Tilman
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Protein Structure and Folding
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416854/
https://ncbi.nlm.nih.gov/pubmed/25784552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.637868
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