Histamine Promotes the Development of Monocyte-Derived Dendritic Cells and Reduces Tumor Growth by Targeting the Myeloid NADPH Oxidase

The efficiency of immune-mediated clearance of cancer cells is hampered by immunosuppressive mediators in the malignant microenvironment, including NADPH oxidase–derived reactive oxygen species. We aimed at defining the effects of histamine, an inhibitor of the myeloid NADPH oxidase/NOX2, on the dev...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Martner, Anna, Wiktorin, Hanna G., Lenox, Brianna, Ewald Sander, Frida, Aydin, Ebru, Aurelius, Johan, Thorén, Fredrik B., Ståhlberg, Anders, Hermodsson, Svante, Hellstrand, Kristoffer
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2015
Assuntos:
Tumor Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416740/
https://ncbi.nlm.nih.gov/pubmed/25870245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402991
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