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Experimental and computational evidence for an essential role of Na(V)1.6 in spike initiation at stretch-sensitive colorectal afferent endings

Stretch-sensitive afferents comprise ∼33% of the pelvic nerve innervation of mouse colorectum, which are activated by colorectal distension and encode visceral nociception. Stretch-sensitive colorectal afferent endings respond tonically to stepped or ramped colorectal stretch, whereas dissociated co...

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Podrobná bibliografie
Vydáno v:J Neurophysiol
Hlavní autoři: Feng, Bin, Zhu, Yi, La, Jun-Ho, Wills, Zachary P., Gebhart, G. F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416596/
https://ncbi.nlm.nih.gov/pubmed/25652923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00717.2014
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