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Shorter telomeres in luminal B, HER-2 and triple-negative breast cancer subtypes
Telomeres are nucleoprotein structures that protect chromosome ends from degradation and recombination. Cancers often have critically shortened telomeres, contributing to genomic instability. Many of these tumors activate telomerase to stabilize telomeric ends and achieve a capacity for unlimited re...
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Pubblicato in: | Mod Pathol |
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Autori principali: | , , , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2010
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4416483/ https://ncbi.nlm.nih.gov/pubmed/21057458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2010.198 |
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