Inhibition of LSD1 reduces herpesvirus infection, shedding, and recurrence by promoting epigenetic suppression of viral genomes

The high prevalence of Herpesviruses in the population and the maintenance of lifelong latent reservoirs are challenges to the control of herpetic diseases, despite the availability of antiviral pharmaceuticals that target viral DNA replication. In addition to oral and genital lesions, herpes simple...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Hill, James M., Quenelle, Debra C., Cardin, Rhonda D., Vogel, Jodi L., Clement, Christian, Bravo, Fernando J., Foster, Timothy P., Bosch-Marce, Marta, Raja, Priya, Lee, Jennifer S., Bernstein, David I., Krause, Philip R., Knipe, David M., Kristie, Thomas M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416407/
https://ncbi.nlm.nih.gov/pubmed/25473037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3010643
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados