A Novel Selective LSD1/KDM1A Inhibitor Epigenetically Blocks Herpes Simplex Virus Lytic Replication and Reactivation from Latency

Cellular processes requiring access to the DNA genome are regulated by an overlay of epigenetic modifications, including histone modification and chromatin remodeling. Similar to the cellular host, many nuclear DNA viruses that depend upon the host cell’s transcriptional machinery are also subject t...

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Bibliografiska uppgifter
Huvudupphovsmän: Liang, Yu, Quenelle, Debra, Vogel, Jodi L., Mascaro, Cristina, Ortega, Alberto, Kristie, Thomas M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Microbiology 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565832/
https://ncbi.nlm.nih.gov/pubmed/23386436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00558-12
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