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Selective inhibition of liver X receptor α-mediated lipogenesis in primary hepatocytes by licochalcone A
BACKGROUND: Sterol regulatory element binding protein-1c (SREBP-1c) is a regulator of the lipogenic pathway and is transcriptionally activated by liver X receptor α (LXRα). This study aims to investigate phytochemicals inhibiting the autonomous transactivity of LXRα with potentials as SREBP-1c inhib...
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| Udgivet i: | Chin Med |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4416341/ https://ncbi.nlm.nih.gov/pubmed/25937827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13020-015-0037-x |
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