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Genetic similarity between cancers and comorbid Mendelian diseases identifies candidate driver genes
Despite large-scale cancer genomics studies, key somatic mutations driving cancer, and their functional roles, remain elusive. Here we propose that analysis of comorbidities of Mendelian diseases with cancers provides a novel, systematic way to discover new cancer genes. If germline genetic variatio...
Tallennettuna:
| Julkaisussa: | Nat Commun |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4416231/ https://ncbi.nlm.nih.gov/pubmed/25926297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8033 |
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