Elevation of Soluble Guanylate Cyclase Suppresses Proliferation and Survival of Human Breast Cancer Cells

Nitric oxide (NO) is an essential signaling molecule in biological systems. Soluble guanylate cyclase (sGC), composing of α1 and β1 subunit, is the receptor for NO. Using radioimmunoassay, we discovered that activation of sGC by treatment with bradykinin or sodium nitroprusside (SNP) is impaired in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wen, Hui-Chin, Chuu, Chih-Pin, Chen, Chen-Yu, Shiah, Shine-Gwo, Kung, Hsing-Jien, King, Kuang-Liang, Su, Liang-Chen, Chang, Shi-Chuan, Chang, Chung-Ho
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416047/
https://ncbi.nlm.nih.gov/pubmed/25928539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125518
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