A Two-Gene Blood Test for Methylated DNA Sensitive for Colorectal Cancer

BACKGROUND: Specific genes are methylated with high frequency in colorectal neoplasia, and may leak into blood. Detection of multiple methylated DNA biomarkers in blood may improve assay sensitivity for colorectal cancer (CRC) relative to a single marker. We undertook a case-control study evaluating...

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Pubblicato in:PLoS One
Autori principali: Pedersen, Susanne K., Baker, Rohan T., McEvoy, Aidan, Murray, David H., Thomas, Melissa, Molloy, Peter L., Mitchell, Sue, Lockett, Trevor, Young, Graeme P., LaPointe, Lawrence C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416022/
https://ncbi.nlm.nih.gov/pubmed/25928810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125041
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