A Two-Gene Blood Test for Methylated DNA Sensitive for Colorectal Cancer

BACKGROUND: Specific genes are methylated with high frequency in colorectal neoplasia, and may leak into blood. Detection of multiple methylated DNA biomarkers in blood may improve assay sensitivity for colorectal cancer (CRC) relative to a single marker. We undertook a case-control study evaluating...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pedersen, Susanne K., Baker, Rohan T., McEvoy, Aidan, Murray, David H., Thomas, Melissa, Molloy, Peter L., Mitchell, Sue, Lockett, Trevor, Young, Graeme P., LaPointe, Lawrence C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416022/
https://ncbi.nlm.nih.gov/pubmed/25928810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125041
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