A Two-Gene Blood Test for Methylated DNA Sensitive for Colorectal Cancer

BACKGROUND: Specific genes are methylated with high frequency in colorectal neoplasia, and may leak into blood. Detection of multiple methylated DNA biomarkers in blood may improve assay sensitivity for colorectal cancer (CRC) relative to a single marker. We undertook a case-control study evaluating...

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Udgivet i:PLoS One
Main Authors: Pedersen, Susanne K., Baker, Rohan T., McEvoy, Aidan, Murray, David H., Thomas, Melissa, Molloy, Peter L., Mitchell, Sue, Lockett, Trevor, Young, Graeme P., LaPointe, Lawrence C.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416022/
https://ncbi.nlm.nih.gov/pubmed/25928810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125041
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