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Dissociation of Learned Helplessness and Fear Conditioning in Mice: A Mouse Model of Depression

The state of being helpless is regarded as a central aspect of depression, and therefore the learned helplessness paradigm in rodents is commonly used as an animal model of depression. The term ‘learned helplessness’ refers to a deficit in escaping from an aversive situation after an animal is expos...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Landgraf, Dominic, Long, Jaimie, Der-Avakian, Andre, Streets, Margo, Welsh, David K.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416012/
https://ncbi.nlm.nih.gov/pubmed/25928892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125892
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