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Curculigoside facilitates fear extinction and prevents depression-like behaviors in a mouse learned helplessness model through increasing hippocampal BDNF

Curculigoside (CUR) is the main active component of traditional Chinese medicine Curculigoorchioides Gaertn (Xianmao in Chinese), which exhibits a variety of pharmacological activities. In this study we investigated the effects of CUR on fear extinction and related depression-like behaviors in mice....

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Yang, San-juan, Song, Zhu-jin, Wang, Xun-cui, Zhang, Zheng-rong, Wu, Sheng-bing, Zhu, Guo-qi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786307/
https://ncbi.nlm.nih.gov/pubmed/31028292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-019-0238-4
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