Oxaliplatin-Induced Peripheral Neuropathy via TRPA1 Stimulation in Mice Dorsal Root Ganglion Is Correlated with Aluminum Accumulation

Oxaliplatin is a platinum-based anticancer drug used to treat metastatic colorectal, breast, and lung cancers. While oxaliplatin kills cancer cells effectively, it exhibits several side effects of varying severity. Neuropathic pain is commonly experienced during treatment with oxaliplatin. Patients...

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Bibliographic Details
Published in:PLoS One
Main Authors: Park, Jin-Hee, Chae, Jisook, Roh, Kangsan, Kil, Eui-Joon, Lee, Minji, Auh, Chung-Kyun, Lee, Myung-Ah, Yeom, Chang-Hwan, Lee, Sukchan
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415919/
https://ncbi.nlm.nih.gov/pubmed/25928068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124875
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