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Regional Hypoxia in Glioblastoma Multiforme Quantified with [(18)F] Fluoromisonidazole Positron Emission Tomography before Radiotherapy: Correlation with Time to Progression and Survival

PURPOSE: Hypoxia is associated with resistance to radiotherapy and chemotherapy and activates transcription factors that support cell survival and migration.We measured the volume of hypoxic tumor and the maximum level of hypoxia in glioblastoma multiforme before radiotherapy with [(18)F]fluoromison...

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Bibliografiset tiedot
Julkaisussa:Clin Cancer Res
Päätekijät: Spence, Alexander M., Muzi, Mark, Swanson, Kristin R., O'Sullivan, Finbarr, Rockhill, Jason K., Rajendran, Joseph G., Adamsen, Tom C.H., Link, Jeanne M., Swanson, Paul E., Yagle, Kevin J., Rostomily, Robert C., Silbergeld, Daniel L., Krohn, Kenneth A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415875/
https://ncbi.nlm.nih.gov/pubmed/18451225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-4995
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