Regional Hypoxia in Glioblastoma Multiforme Quantified with [(18)F] Fluoromisonidazole Positron Emission Tomography before Radiotherapy: Correlation with Time to Progression and Survival

PURPOSE: Hypoxia is associated with resistance to radiotherapy and chemotherapy and activates transcription factors that support cell survival and migration.We measured the volume of hypoxic tumor and the maximum level of hypoxia in glioblastoma multiforme before radiotherapy with [(18)F]fluoromison...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Spence, Alexander M., Muzi, Mark, Swanson, Kristin R., O'Sullivan, Finbarr, Rockhill, Jason K., Rajendran, Joseph G., Adamsen, Tom C.H., Link, Jeanne M., Swanson, Paul E., Yagle, Kevin J., Rostomily, Robert C., Silbergeld, Daniel L., Krohn, Kenneth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415875/
https://ncbi.nlm.nih.gov/pubmed/18451225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-4995
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