Regional Hypoxia in Glioblastoma Multiforme Quantified with [(18)F] Fluoromisonidazole Positron Emission Tomography before Radiotherapy: Correlation with Time to Progression and Survival

PURPOSE: Hypoxia is associated with resistance to radiotherapy and chemotherapy and activates transcription factors that support cell survival and migration.We measured the volume of hypoxic tumor and the maximum level of hypoxia in glioblastoma multiforme before radiotherapy with [(18)F]fluoromison...

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發表在:Clin Cancer Res
Main Authors: Spence, Alexander M., Muzi, Mark, Swanson, Kristin R., O'Sullivan, Finbarr, Rockhill, Jason K., Rajendran, Joseph G., Adamsen, Tom C.H., Link, Jeanne M., Swanson, Paul E., Yagle, Kevin J., Rostomily, Robert C., Silbergeld, Daniel L., Krohn, Kenneth A.
格式: Artigo
語言:Inglês
出版: 2008
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415875/
https://ncbi.nlm.nih.gov/pubmed/18451225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-4995
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