Enhanced tethered-flight duration and locomotor activity by overexpression of the human gene SOD1 in Drosophila motorneurons

Mutation of the human gene superoxide dismutase (hSOD1) is associated with the fatal neurodegenerative disease familial amyotrophic lateral sclerosis (Lou Gehrig’s disease). Selective overexpression of hSOD1 in Drosophila motorneurons increases lifespan to 140% of normal. The current study was desig...

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Bibliographische Detailangaben
Veröffentlicht in:Genet Mol Biol
Hauptverfasser: Petrosyan, Agavni, Hsieh, I-Hui, Phillips, John P., Saberi, Kourosh
Format: Artigo
Sprache:Inglês
Veröffentlicht: Sociedade Brasileira de Genética 2015
Schlagworte:
Cellular, Molecular and Developmental Genetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415569/
https://ncbi.nlm.nih.gov/pubmed/25983632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1415-475738138120140132
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