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Modular Degradable Hydrogels Based on Thiol-Reactive Oxanorbornadiene Linkers

[Image: see text] Oxanorbornadiene dicarboxylate (OND) reagents are potent Michael acceptors, the adducts of which undergo fragmentation by retro-Diels–Alder reaction at rates that vary with the substitution pattern on the OND moiety. Rapid conjugate addition between thiol-terminated tetravalent PEG...

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Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: Higginson, Cody J., Kim, Seung Yeon, Peláez-Fernández, Miguel, Fernández-Nieves, Alberto, Finn, M.G.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2015
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415036/
https://ncbi.nlm.nih.gov/pubmed/25871459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b02708
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