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Z-Selective Olefin Synthesis via Iron-Catalyzed Reductive Coupling of Alkyl Halides with Terminal Arylalkynes

[Image: see text] Selective catalytic synthesis of Z-olefins has been challenging. Here we describe a method to produce 1,2-disubstituted olefins in high Z selectivity via reductive cross-coupling of alkyl halides with terminal arylalkynes. The method employs inexpensive and nontoxic catalyst (iron(...

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Pubblicato in:J Am Chem Soc
Autori principali: Cheung, Chi Wai, Zhurkin, Fedor E., Hu, Xile
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2015
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415033/
https://ncbi.nlm.nih.gov/pubmed/25831473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b01784
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