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Amine synthesis via iron-catalysed reductive coupling of nitroarenes with alkyl halides

(Hetero)Aryl amines, an important class of organic molecules in medicinal chemistry, are most commonly synthesized from anilines, which are in turn synthesized by hydrogenation of nitroarenes. Amine synthesis directly from nitroarenes is attractive due to improved step economy and functional group c...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Cheung, Chi Wai, Hu, Xile
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990657/
https://ncbi.nlm.nih.gov/pubmed/27515391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12494
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