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Agalactosyl glycoforms of IgG autoantibodies are pathogenic.

The glycosylation of IgG results in many different glycoforms. A large body of correlative data (including remission of arthritis during pregnancy) has suggested that IgG molecules lacking galactose were associated with rheumatoid arthritis. We now demonstrate that agalactosyl IgG glycoforms are dir...

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Bibliographic Details
Main Authors: Rademacher, T W, Williams, P, Dwek, R A
Format: Artigo
Language:Inglês
Published: 1994
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC44150/
https://ncbi.nlm.nih.gov/pubmed/8016124
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