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Agalactosyl glycoforms of IgG autoantibodies are pathogenic.

The glycosylation of IgG results in many different glycoforms. A large body of correlative data (including remission of arthritis during pregnancy) has suggested that IgG molecules lacking galactose were associated with rheumatoid arthritis. We now demonstrate that agalactosyl IgG glycoforms are dir...

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Detalhes bibliográficos
Main Authors: Rademacher, T W, Williams, P, Dwek, R A
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC44150/
https://ncbi.nlm.nih.gov/pubmed/8016124
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