Antitumor effector B cells directly kill tumor cells via the Fas/FasL pathway and are regulated by IL-10

We have previously reported that adoptive transfer of tumor-draining lymph node (TDLN) B cells confers tumor regression in a spontaneous pulmonary metastasis mouse model of breast cancer. In this study, we identified IL-10-producing cells within these B cells, and found that IL-10 removal, either by...

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Gepubliceerd in:Eur J Immunol
Hoofdauteurs: Tao, Huimin, Lu, Lin, Xia, Yang, Dai, Fu, Wang, Yi, Bao, Yangyi, Lundy, Steven K., Ito, Fumito, Pan, Qin, Zhang, Xiaolian, Zheng, Fang, Shu, Guoshun, Fang, Bingmu, Jiang, Jinhong, Xia, Jianchuang, Huang, Shiang, Li, Qiao, Chang, Alfred E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414939/
https://ncbi.nlm.nih.gov/pubmed/25545618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201444625
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