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Aromatic Hydroxylation of Salicylic Acid and Aspirin by Human Cytochromes P450
Aspirin (acetylsalicylic acid) is a well-known and widely-used analgesic. It is rapidly deacetylated to salicylic acid, which forms two hippuric acids—salicyluric acid and gentisuric acid—and two glucuronides. The oxidation of aspirin and salicylic acid has been reported with human liver microsomes,...
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| Publicado en: | Eur J Pharm Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4414920/ https://ncbi.nlm.nih.gov/pubmed/25840124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejps.2015.03.015 |
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