Abnormal contractile properties of muscle fibers expressing beta-myosin heavy chain gene mutations in patients with hypertrophic cardiomyopathy.

Missense mutations in the beta-myosin heavy chain (beta-MHC) gene cause hypertrophic cardiomyopathy (HCM). As normal and mutant beta-MHCs are expressed in slow-twitch skeletal muscle of HCM patients, we compared the contractile properties of single slow-twitch muscle fibers from patients with three...

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I whakaputaina i:	J Clin Invest
Ngā kaituhi matua:	Lankford, E B, Epstein, N D, Fananapazir, L, Sweeney, H L
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	American Society for Clinical Investigation 1995
Ngā marau:	Research Article
Urunga tuihono:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC441484/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7883988/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117795
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