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Somatic mutation of human immunoglobulin V genes in the X-linked HyperIgM syndrome.

Somatic mutation of Ig variable regions occurs prominently in germinal centers, but it has been debated whether the mutation process initiates in germinal centers or is activated before germinal center entry of B cells. We have analyzed for the presence of somatic mutation in Ig gene rearrangements...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chu, Y W, Marin, E, Fuleihan, R, Ramesh, N, Rosen, F S, Geha, R S, Insel, R A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1995
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC441480/
https://ncbi.nlm.nih.gov/pubmed/7533792
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