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Induction of sustained expression of proto-oncogene c-fms by platelet-derived growth factor, epidermal growth factor, and basic fibroblast growth factor, and its suppression by interferon-gamma and macrophage colony-stimulating factor in human aortic medial smooth muscle cells.

Vascular medial smooth muscle cells migrate, proliferate and transform to foam cells in the process of atherosclerosis. We have reported that the intimal smooth muscle cells express proto-oncogene c-fms, a characteristic gene of monocyte-macrophages, which is not normally expressed in medial smooth...

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Pubblicato in:J Clin Invest
Autori principali: Inaba, T, Gotoda, T, Harada, K, Shimada, M, Ohsuga, J, Ishibashi, S, Yazaki, Y, Yamada, N
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1995
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC441450/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7883962/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117761
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