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Induction of sustained expression of proto-oncogene c-fms by platelet-derived growth factor, epidermal growth factor, and basic fibroblast growth factor, and its suppression by interferon-gamma and macrophage colony-stimulating factor in human aortic medial smooth muscle cells.

Vascular medial smooth muscle cells migrate, proliferate and transform to foam cells in the process of atherosclerosis. We have reported that the intimal smooth muscle cells express proto-oncogene c-fms, a characteristic gene of monocyte-macrophages, which is not normally expressed in medial smooth...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Inaba, T, Gotoda, T, Harada, K, Shimada, M, Ohsuga, J, Ishibashi, S, Yazaki, Y, Yamada, N
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC441450/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7883962/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117761
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