Susceptibility to tuberculosis is associated with variants in the ASAP1 gene encoding a regulator of dendritic cell migration

Human genetic factors predispose to tuberculosis (TB). We studied 7.6 million genetic variants in 5,530 pulmonary TB patients and 5,607 healthy controls. In the combined analysis of these subjects and the follow-up cohort (15,087 TB patients and controls altogether), we found association between TB...

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Опубликовано в: :Nat Genet
Главные авторы: Curtis, James, Luo, Yang, Zenner, Helen L., Cuchet-Lourenço, Delphine, Wu, Changxin, Lo, Kitty, Maes, Mailis, Alisaac, Ali, Stebbings, Emma, Liu, Jimmy Z., Kopanitsa, Liliya, Ignatyeva, Olga, Balabanova, Yanina, Nikolayevskyy, Vladyslav, Baessmann, Ingelore, Thye, Thorsten, Meyer, Christian G., Nürnberg, Peter, Horstmann, Rolf D., Drobniewski, Francis, Plagnol, Vincent, Barrett, Jeffrey C., Nejentsev, Sergey
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414475/
https://ncbi.nlm.nih.gov/pubmed/25774636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3248
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