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INSULIN-DEGRADING ENZYME SORTING IN EXOSOMES: A SECRETORY PATHWAY FOR A KEY BRAIN Aβ-DEGRADING PROTEASE
The accumulation of Aβ peptides in the senile plaques is one of the hallmarks of Alzheimer disease (AD) progression. The endocytic pathway has been proposed as a major subcellular site for Aβ generation while the compartments in which Aβ-degrading proteases interact with Aβ are still elusive. It was...
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| Publicado no: | J Alzheimers Dis |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4414343/ https://ncbi.nlm.nih.gov/pubmed/20061628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-1206 |
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