PSMA-targeted SPECT agents: Mode of Binding effect on in vitro Performance

BACKGROUND: The enzyme-biomarker prostate-specific membrane antigen (PSMA) is an active target for imaging and therapeutic applications for prostate cancer. The internalization of PSMA has been shown to vary with inhibitors’ mode of binding: irreversible, slowly reversible and reversible. METHODS: I...

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Dettagli Bibliografici
Pubblicato in:Prostate
Autori principali: Nedrow-Byers, Jessie R., Moore, Adam L., Ganguly, Tanushree, Hopkins, Mark R., Fulton, Melody D., Benny, Paul, Berkman, Clifford E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414331/
https://ncbi.nlm.nih.gov/pubmed/22911263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22575
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