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Control of the MYC-eIF4E axis plus mTOR inhibitor treatment in small cell lung cancer

BACKGROUND: Mammalian target of rapamycin (mTOR) inhibitors have anti-tumor effects against renal cell carcinoma, pancreatic neuroendocrine cancer and breast cancer. In this study, we analyzed the antitumor effects of mTOR inhibitors in small cell lung cancer (SCLC) cells and sought to clarify the m...

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Bibliografske podrobnosti
izdano v:BMC Cancer
Main Authors: Matsumoto, Masaru, Seike, Masahiro, Noro, Rintaro, Soeno, Chie, Sugano, Teppei, Takeuchi, Susumu, Miyanaga, Akihiko, Kitamura, Kazuhiro, Kubota, Kaoru, Gemma, Akihiko
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414307/
https://ncbi.nlm.nih.gov/pubmed/25884680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1202-4
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