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Asparaginase induces apoptosis and cytoprotective autophagy in chronic myeloid leukemia cells

The antitumor enzyme asparaginase, which targets essential amino acid L-asparagine and catalyzes it to L-aspartic acid and ammonia, has been used for years in the treatment of acute lymphoblastic leukemia (ALL), subtypes of myeloid leukemia and T-cell lymphomas, whereas the anti-chronic myeloid leuk...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Song, Ping, Ye, Li, Fan, Jiajun, Li, Yubin, Zeng, Xian, Wang, Ziyu, Wang, Shaofei, Zhang, Guoping, Yang, Ping, Cao, Zhonglian, Ju, Dianwen
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414159/
https://ncbi.nlm.nih.gov/pubmed/25738356
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